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Identification of an Unfolding Intermediate for a DNA Lesion Bypass Polymerase

Sulfolobus solfataricusDNA Polymerase IV (Dpo4), a prototype Y-family DNA polymerase, has been well characterized biochemically and biophysically at 37 °C or lower temperatures. However, the physiological temperature of the hyperthermophile S. solfataricus is approximately 80 °C. With such a large d...

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Autores principales: Sherrer, Shanen M., Maxwell, Brian A., Pack, Lindsey R., Fiala, Kevin A., Fowler, Jason D., Zhang, Jun, Suo, Zucai
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398204/
https://ncbi.nlm.nih.gov/pubmed/22667759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3002115
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