Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases

Higher eukaryotes encode various Y-family DNA polymerases to perform global DNA lesion bypass. To provide complete mutation spectra for abasic lesion bypass, we employed short oligonucleotide sequencing assays to determine the sequences of abasic lesion bypass products synthesized by human Y-family...

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Bibliographic Details
Main Authors: Sherrer, Shanen M., Fiala, Kevin A., Fowler, Jason D., Newmister, Sean A., Pryor, John M., Suo, Zucai
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025555/
https://ncbi.nlm.nih.gov/pubmed/20846959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq719
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