Determinants of eukaryal cell killing by the bacterial ribotoxin PrrC

tRNA damage inflicted by the Escherichia coli anticodon nuclease PrrC (EcoPrrC) underlies an antiviral response to phage T4 infection. PrrC homologs are present in many bacterial proteomes, though their biological activities are uncharted. PrrCs consist of two domains: an N-terminal NTPase module re...

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Bibliographic Details
Main Authors: Meineke, Birthe, Schwer, Beate, Schaffrath, Raffael, Shuman, Stewart
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025547/
https://ncbi.nlm.nih.gov/pubmed/20855293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq831
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