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Determinants of the cytotoxicity of PrrC anticodon nuclease and its amelioration by tRNA repair
Breakage of tRNA(Lys(UUU)) by the Escherichia coli anticodon nuclease PrrC (EcoPrrC) underlies a host antiviral response to phage T4 infection that is ultimately thwarted by a virus-encoded RNA repair system. PrrC homologs are prevalent in other bacteria, but their activities and substrates are not...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261736/ https://ncbi.nlm.nih.gov/pubmed/22101242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.030171.111 |
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