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Structure-function relations in the NTPase domain of the antiviral tRNA ribotoxin Escherichia coli PrrC
Breakage of tRNA by Escherichia coli anticodon nuclease PrrC (EcoPrrC) underlies a host antiviral response to phage T4 infection. Expression of EcoPrrC is cytocidal in yeast, signifying that PrrC ribotoxicity crosses phylogenetic domain boundaries. EcoPrrC consists of an N-terminal NTPase module tha...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312988/ https://ncbi.nlm.nih.gov/pubmed/22386822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.02.008 |
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