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A fungal anticodon nuclease ribotoxin exploits a secondary cleavage site to evade tRNA repair
PaOrf2 and γ-toxin subunits of Pichia acaciae toxin (PaT) and Kluyveromyces lactis zymocin are tRNA anticodon nucleases. These secreted ribotoxins are assimilated by Saccharomyces cerevisiae, wherein they arrest growth by depleting specific tRNAs. Toxicity can be recapitulated by induced intracellul...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3425785/ https://ncbi.nlm.nih.gov/pubmed/22836353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.034132.112 |
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