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DNA Damage Responses Are Induced by tRNA Anticodon Nucleases and Hygromycin B

Previous studies revealed DNA damage to occur during the toxic action of PaT, a fungal anticodon ribonuclease (ACNase) targeting the translation machinery via tRNA cleavage. Here, we demonstrate that other translational stressors induce DNA damage-like responses in yeast as well: not only zymocin, a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wemhoff, Sabrina, Klassen, Roland, Beetz, Anja, Meinhardt, Friedhelm
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966947/
https://ncbi.nlm.nih.gov/pubmed/27472060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157611
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