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Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signaling

Previous work in yeast has suggested that modification of tRNAs, in particular uridine bases in the anticodon wobble position (U34), is linked to TOR (target of rapamycin) signaling. Hence, U34 modification mutants were found to be hypersensitive to TOR inhibition by rapamycin. To study whether this...

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書誌詳細
出版年:Microb Cell
主要な著者: Scheidt, Viktor, Jüdes, André, Bär, Christian, Klassen, Roland, Schaffrath, Raffael
フォーマット: Artigo
言語:Inglês
出版事項: Shared Science Publishers OG 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349137/
https://ncbi.nlm.nih.gov/pubmed/28357221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2014.12.179
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