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Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signaling

Previous work in yeast has suggested that modification of tRNAs, in particular uridine bases in the anticodon wobble position (U34), is linked to TOR (target of rapamycin) signaling. Hence, U34 modification mutants were found to be hypersensitive to TOR inhibition by rapamycin. To study whether this...

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Vydáno v:Microb Cell
Hlavní autoři: Scheidt, Viktor, Jüdes, André, Bär, Christian, Klassen, Roland, Schaffrath, Raffael
Médium: Artigo
Jazyk:Inglês
Vydáno: Shared Science Publishers OG 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349137/
https://ncbi.nlm.nih.gov/pubmed/28357221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2014.12.179
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