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Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signaling

Previous work in yeast has suggested that modification of tRNAs, in particular uridine bases in the anticodon wobble position (U34), is linked to TOR (target of rapamycin) signaling. Hence, U34 modification mutants were found to be hypersensitive to TOR inhibition by rapamycin. To study whether this...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Microb Cell
Prif Awduron: Scheidt, Viktor, Jüdes, André, Bär, Christian, Klassen, Roland, Schaffrath, Raffael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shared Science Publishers OG 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349137/
https://ncbi.nlm.nih.gov/pubmed/28357221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2014.12.179
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