The t(6)A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans

Endoribonuclease toxins (ribotoxins) are produced by bacteria and fungi to respond to stress, eliminate non-self competitor species, or interdict virus infection. PrrC is a bacterial ribotoxin that targets and cleaves tRNA(Lys) (UUU) in the anticodon loop. In vitro studies suggested that the post-tr...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:RNA Biol
Autori principali: Bacusmo, Jo Marie, Orsini, Silvia S., Hu, Jennifer, DeMott, Michael, Thiaville, Patrick C., Elfarash, Ameer, Paulines, Mellie June, Rojas-Benítez, Diego, Meineke, Birthe, Deutsch, Chris, Iwata-Reuyl, Dirk, Limbach, Patrick A., Dedon, Peter C., Rice, Kelly C., Shuman, Stewart, de Crécy-Lagard, Valérie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Review - Solicited
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103680/
https://ncbi.nlm.nih.gov/pubmed/28726545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1353861
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