ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa

Compounds that inhibit signalling upstream of ERK (extracellular-signal-regulated kinase) are promising anticancer therapies, motivating research to define how this pathway promotes cancers. In the present study, we show that human capicúa represses mRNA expression for PEA3 (polyoma enhancer activat...

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Bibliographic Details
Main Authors: Dissanayake, Kumara, Toth, Rachel, Blakey, Jamie, Olsson, Olof, Campbell, David G., Prescott, Alan R., MacKintosh, Carol
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025492/
https://ncbi.nlm.nih.gov/pubmed/21087211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101562
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