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ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa

Compounds that inhibit signalling upstream of ERK (extracellular-signal-regulated kinase) are promising anticancer therapies, motivating research to define how this pathway promotes cancers. In the present study, we show that human capicúa represses mRNA expression for PEA3 (polyoma enhancer activat...

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Detalhes bibliográficos
Main Authors: Dissanayake, Kumara, Toth, Rachel, Blakey, Jamie, Olsson, Olof, Campbell, David G., Prescott, Alan R., MacKintosh, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025492/
https://ncbi.nlm.nih.gov/pubmed/21087211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101562
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