Inactivation of Transcriptional Repressor Capicua Confers Sorafenib Resistance in Human Hepatocellular Carcinoma

BACKGROUND & AIMS: Sorafenib is a multireceptor tyrosine kinase inhibitor that can prolong overall survival in patients with advanced hepatocellular carcinoma (HCC). Although most HCC patients who receive sorafenib ultimately show disease progression, it still is unclear whether and how HCC cell...

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Dades bibliogràfiques
Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Hashiba, Tomomi, Yamashita, Taro, Okada, Hikari, Nio, Kouki, Hayashi, Takehiro, Asahina, Yoshiro, Hayashi, Tomoyuki, Terashima, Takeshi, Iida, Noriho, Takatori, Hajime, Shimakami, Tetsuro, Kawaguchi, Kazunori, Arai, Kuniaki, Sakai, Yoshio, Yamashita, Tatsuya, Mizukoshi, Eishiro, Takamura, Hiroyuki, Ohta, Tetsuo, Honda, Masao, Kaneko, Shuichi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305345/
https://ncbi.nlm.nih.gov/pubmed/32169577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.02.009
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