Inactivation of Transcriptional Repressor Capicua Confers Sorafenib Resistance in Human Hepatocellular Carcinoma

BACKGROUND & AIMS: Sorafenib is a multireceptor tyrosine kinase inhibitor that can prolong overall survival in patients with advanced hepatocellular carcinoma (HCC). Although most HCC patients who receive sorafenib ultimately show disease progression, it still is unclear whether and how HCC cell...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Mol Gastroenterol Hepatol
Main Authors: Hashiba, Tomomi, Yamashita, Taro, Okada, Hikari, Nio, Kouki, Hayashi, Takehiro, Asahina, Yoshiro, Hayashi, Tomoyuki, Terashima, Takeshi, Iida, Noriho, Takatori, Hajime, Shimakami, Tetsuro, Kawaguchi, Kazunori, Arai, Kuniaki, Sakai, Yoshio, Yamashita, Tatsuya, Mizukoshi, Eishiro, Takamura, Hiroyuki, Ohta, Tetsuo, Honda, Masao, Kaneko, Shuichi
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305345/
https://ncbi.nlm.nih.gov/pubmed/32169577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.02.009
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