Inactivation of Transcriptional Repressor Capicua Confers Sorafenib Resistance in Human Hepatocellular Carcinoma

BACKGROUND & AIMS: Sorafenib is a multireceptor tyrosine kinase inhibitor that can prolong overall survival in patients with advanced hepatocellular carcinoma (HCC). Although most HCC patients who receive sorafenib ultimately show disease progression, it still is unclear whether and how HCC cell...

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Vydáno v:Cell Mol Gastroenterol Hepatol
Hlavní autoři: Hashiba, Tomomi, Yamashita, Taro, Okada, Hikari, Nio, Kouki, Hayashi, Takehiro, Asahina, Yoshiro, Hayashi, Tomoyuki, Terashima, Takeshi, Iida, Noriho, Takatori, Hajime, Shimakami, Tetsuro, Kawaguchi, Kazunori, Arai, Kuniaki, Sakai, Yoshio, Yamashita, Tatsuya, Mizukoshi, Eishiro, Takamura, Hiroyuki, Ohta, Tetsuo, Honda, Masao, Kaneko, Shuichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305345/
https://ncbi.nlm.nih.gov/pubmed/32169577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.02.009
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