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Effect of IRS4 Levels on PI 3-Kinase Signalling

Insulin receptor substrate 1 (IRS1) and IRS2 are well-characterized adapter proteins that relay signals from receptor tyrosine kinases to downstream components of signalling pathways. In contrast, the function of IRS4 is not well understood. IRS4 overexpression has been associated with acute lymphob...

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Autors principals: Hoxhaj, Gerta, Dissanayake, Kumara, MacKintosh, Carol
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769281/
https://ncbi.nlm.nih.gov/pubmed/24039912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073327
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