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A powerful hybrid approach to select top single-nucleotide polymorphisms for genome-wide association study

BACKGROUND: Genome-wide association (GWA) study has recently become a powerful approach for detecting genetic variants for common diseases without prior knowledge of the variant's location or function. Generally, in GWA studies, the most significant single-nucleotide polymorphisms (SNPs) associ...

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Hlavní autoři: Wang, Jian, Shete, Sanjay
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024976/
https://ncbi.nlm.nih.gov/pubmed/21211033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-12-3
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