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False-Negative-Rate Based Approach for Selecting Top Single-Nucleotide Polymorphisms in the First Stage of a Two-Stage Genome-Wide Association Study

Genome-wide association (GWA) studies, where hundreds of thousands of single-nucleotide polymorphisms (SNPs) are tested simultaneously, are becoming popular for identifying disease loci for common diseases. Most commonly, a GWA study involves two stages: the first stage includes testing the associat...

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Hlavní autoři: Huang, Zhuying, Wang, Jian, Wu, Chih-Chieh, Houlston, Richard S., Bondy, Melissa L., Shete, Sanjay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467022/
https://ncbi.nlm.nih.gov/pubmed/23060946
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