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A New Approach to Account for the Correlations among Single Nucleotide Polymorphisms in Genome-Wide Association Studies

In genetic association studies, such as genome-wide association studies (GWAS), the number of single nucleotide polymorphisms (SNPs) can be as large as hundreds of thousands. Due to linkage disequilibrium, many SNPs are highly correlated; assuming they are independent is not valid. The commonly used...

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Detalhes bibliográficos
Main Authors: Chen, Zhongxue, Liu, Qingzhong
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171280/
https://ncbi.nlm.nih.gov/pubmed/21849789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330135
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