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A New Approach to Account for the Correlations among Single Nucleotide Polymorphisms in Genome-Wide Association Studies
In genetic association studies, such as genome-wide association studies (GWAS), the number of single nucleotide polymorphisms (SNPs) can be as large as hundreds of thousands. Due to linkage disequilibrium, many SNPs are highly correlated; assuming they are independent is not valid. The commonly used...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
S. Karger AG
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171280/ https://ncbi.nlm.nih.gov/pubmed/21849789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330135 |
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