Modulation of RNA polymerase activity through trigger loop folding

Folding of the trigger loop of RNA polymerase promotes nucleotide addition through creating a closed, catalytically competent conformation of the active center. Here, we discuss the impact of adjacent RNA polymerase elements, including the F loop and the jaw domain, as well as external regulatory fa...

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Main Authors: Miropolskaya, Nataliya, Nikiforov, Vadim, Klimašauskas, Saulius, Artsimovitch, Irina, Kulbachinskiy, Andrey
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023635/
https://ncbi.nlm.nih.gov/pubmed/21326898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.1.2.12544
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https://ncbi.nlm.nih.gov/pmc/articles/PMC3023635/
https://ncbi.nlm.nih.gov/pubmed/21326898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.1.2.12544

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