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DC expressing transgene Foxp3 are regulatory APC
Tolerogenic dendritic cells (DC) and suppressive Foxp3(+) Treg play important roles in preventing autoimmunity and allograft rejection. We report that (adenovirus-mediated) ectopic expression of Foxp3 in human DC (i.e. DC.Foxp3) yields an antigen presenting cell (APC) that severe limits T cell proli...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023581/ https://ncbi.nlm.nih.gov/pubmed/19941313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939667 |
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