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Ectopic T-bet expression licenses dendritic cells for interleukin (IL)-12-independent priming of Type-1 T cells in vitro
T-bet (TBX21) is a transcription factor required for the optimal development of Type-1 immune responses. While initially characterized for its intrinsic role in T cell functional polarization, endogenous T-bet may also be critical to the licensing of Type-1-biasing antigen presenting cells. Here, we...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921905/ https://ncbi.nlm.nih.gov/pubmed/19915058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901477 |
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