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Uptake of apoptotic DC converts immature DC into tolerogenic DC, which induce differentiation of Foxp3+ regulatory T cells

Dendritic cell (DC) apoptosis has been observed in patients with cancer and sepsis, and defects in DC apoptosis have been implicated in development of autoimmune diseases. The mechanisms of how DC apoptosis affects immune responses however, are unclear. In this study we showed that immature viable D...

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Bibliographic Details
Published in:Eur J Immunol
Main Authors: Kushwah, Rahul, Wu, Jing, Oliver, Jordan R., Jiang, George, Zhang, Jinyi, Siminovitch, Katherine A., Hu, Jim
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603937/
https://ncbi.nlm.nih.gov/pubmed/20101618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939782
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