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Chymotrypsin C Is a Co-activator of Human Pancreatic Procarboxypeptidases A1 and A2
Human digestive carboxypeptidases CPA1, CPA2, and CPB1 are secreted by the pancreas as inactive proenzymes containing a 94–96-amino acid-long propeptide. Activation of procarboxypeptidases is initiated by proteolytic cleavage at the C-terminal end of the propeptide by trypsin. Here, we demonstrate t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023477/ https://ncbi.nlm.nih.gov/pubmed/21098023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.187369 |
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