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Calcium Dynamics in the Ventricular Myocytes of SERCA2 Knockout Mice: A Modeling Study
We describe a simulation study of Ca(2+) dynamics in mice with cardiomyocyte-specific conditional excision of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) gene, using an experimental data-driven biophysically-based modeling framework. Previously, we reported a moderately impaired heart fu...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021663/ https://ncbi.nlm.nih.gov/pubmed/21244828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.048 |
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