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Calcium Dynamics in the Ventricular Myocytes of SERCA2 Knockout Mice: A Modeling Study

We describe a simulation study of Ca(2+) dynamics in mice with cardiomyocyte-specific conditional excision of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) gene, using an experimental data-driven biophysically-based modeling framework. Previously, we reported a moderately impaired heart fu...

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Bibliografische gegevens
Hoofdauteurs: Li, L., Louch, W.E., Niederer, S.A., Andersson, K.B., Christensen, G., Sejersted, O.M., Smith, N.P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021663/
https://ncbi.nlm.nih.gov/pubmed/21244828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.048
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