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Sodium Accumulation in SERCA Knockout-Induced Heart Failure
In cardiomyocytes, a major decrease in the level of sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) can severely impair systolic and diastolic functions. In mice with cardiomyocyte-specific conditional excision of the Serca2 gene (SERCA2 KO), end-stage heart failure developed between four and seve...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341551/ https://ncbi.nlm.nih.gov/pubmed/22824267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.045 |
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