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Multiscale Modeling of Calcium Cycling in Cardiac Ventricular Myocyte: Macroscopic Consequences of Microscopic Dyadic Function

In cardiac ventricular myocytes, calcium (Ca) release occurs at distinct structures (dyads) along t-tubules, where L-type Ca channels (LCCs) appose sarcoplasmic reticulum (SR) Ca release channels (RyR2s). We developed a model of the cardiac ventricular myocyte that simulates local stochastic Ca rele...

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Bibliografiset tiedot
Päätekijät: Gaur, Namit, Rudy, Yoram
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123916/
https://ncbi.nlm.nih.gov/pubmed/21689523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.031
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