Increasing Cardiac Contractility After Myocardial Infarction Exacerbates Cardiac Injury and Pump Dysfunction

RATIONALE: Myocardial infarction (MI) leads to heart failure (HF) and premature death. The respective roles of myocyte death and depressed myocyte contractility in the induction of HF after MI have not been clearly defined and are the focus of this study. OBJECTIVES: We developed a mouse model in wh...

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Autors principals: Zhang, Hongyu, Chen, Xiongwen, Gao, Erhe, MacDonnell, Scott M., Wang, Wei, Kolpakov, Mikhail, Nakayama, Hiroyuki, Zhang, Xiaoying, Jaleel, Naser, Harris, David M., Li, Yingxin, Tang, Mingxin, Berretta, Remus, Leri, Annarosa, Kajstura, Jan, Sabri, Abdelkarim, Koch, Walter J., Molkentin, Jeffery D., Houser, Steven R.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021375/
https://ncbi.nlm.nih.gov/pubmed/20671241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.219220
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