Increasing Cardiac Contractility After Myocardial Infarction Exacerbates Cardiac Injury and Pump Dysfunction

RATIONALE: Myocardial infarction (MI) leads to heart failure (HF) and premature death. The respective roles of myocyte death and depressed myocyte contractility in the induction of HF after MI have not been clearly defined and are the focus of this study. OBJECTIVES: We developed a mouse model in wh...

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Bibliografiske detaljer
Main Authors: Zhang, Hongyu, Chen, Xiongwen, Gao, Erhe, MacDonnell, Scott M., Wang, Wei, Kolpakov, Mikhail, Nakayama, Hiroyuki, Zhang, Xiaoying, Jaleel, Naser, Harris, David M., Li, Yingxin, Tang, Mingxin, Berretta, Remus, Leri, Annarosa, Kajstura, Jan, Sabri, Abdelkarim, Koch, Walter J., Molkentin, Jeffery D., Houser, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021375/
https://ncbi.nlm.nih.gov/pubmed/20671241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.219220
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