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IL-8-INDUCED NEUTROPHIL CHEMOTAXIS IS MEDIATED BY JANUS KINASE 3 (JAK3)
Janus kinase 3 (JAK3) is a non-receptor tyrosine kinase vital to the regulation of T-cells. We report that JAK3 is a mediator of IL-8 stimulation of a different class of hematopoietic relevant cells: human neutrophils. IL-8 induced a time- and concentration-dependent activation of JAK3 activity in n...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021320/ https://ncbi.nlm.nih.gov/pubmed/21095188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.11.031 |
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