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Species-Dependent Differences in Cofactor Utilization for Formation of the Protease-Resistant Prion Protein in Vitro

The cofactor preferences for in vitro propagation of the protease-resistant isoforms of the prion protein (PrP(Sc)) from various rodent species were investigated using the serial protein misfolding cyclic amplification (sPMCA) technique. Whereas RNA molecules facilitate hamster PrP(Sc) propagation,...

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Autors principals: Deleault, Nathan R., Kascsak, Richard, Geoghegan, James C., Supattapone, Surachai
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021175/
https://ncbi.nlm.nih.gov/pubmed/20377181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100370b
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