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Subunit-specific degradation of the UmuD/D′ heterodimer by the ClpXP protease: the role of trans recognition in UmuD′ stability
The Escherichia coli UmuD′ protein is a subunit of the recently described error-prone DNA polymerase, pol V. UmuD′ is initially synthesized as an unstable and mutagenically inactive pro-protein, UmuD. Upon processing, UmuD′ assumes a relatively stable conformation and becomes mutagenically active. W...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2000
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302103/ https://ncbi.nlm.nih.gov/pubmed/11013227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.19.5251 |
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