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Subunit-specific degradation of the UmuD/D′ heterodimer by the ClpXP protease: the role of trans recognition in UmuD′ stability
The Escherichia coli UmuD′ protein is a subunit of the recently described error-prone DNA polymerase, pol V. UmuD′ is initially synthesized as an unstable and mutagenically inactive pro-protein, UmuD. Upon processing, UmuD′ assumes a relatively stable conformation and becomes mutagenically active. W...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302103/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11013227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.19.5251 |
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