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The Role of the BMP Signaling Antagonist Noggin in the Development of Prostate Cancer Osteolytic Bone Metastasis

Members of the BMP and Wnt protein families play a relevant role in physiologic and pathologic bone turnover. Extracellular antagonists are crucial for the modulation of their activity. Lack of expression of the BMP antagonist noggin by osteoinductive, carcinoma-derived cell lines is a determinant o...

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Autors principals: Secondini, Chiara, Wetterwald, Antoinette, Schwaninger, Ruth, Thalmann, George N., Cecchini, Marco G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020964/
https://ncbi.nlm.nih.gov/pubmed/21249149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016078
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