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BMP7, a Putative Regulator of Epithelial Homeostasis in the Human Prostate, Is a Potent Inhibitor of Prostate Cancer Bone Metastasis in Vivo

Bone morphogenic protein 7 (BMP7) counteracts physiological epithelial-to-mesenchymal transition, a process that is indicative of epithelial plasticity. Because epithelial-to-mesenchymal transition is involved in cancer, we investigated whether BMP7 plays a role in prostate cancer growth and metasta...

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Detalhes bibliográficos
Main Authors: Buijs, Jeroen T., Rentsch, Cyrill A., van der Horst, Geertje, van Overveld, Petra G.M., Wetterwald, Antoinette, Schwaninger, Ruth, Henriquez, Niek V., ten Dijke, Peter, Borovecki, Fran, Markwalder, Regula, Thalmann, George N., Papapoulos, Socrates E., Pelger, Rob C.M., Vukicevic, Slobodan, Cecchini, Marco G., Löwik, Clemens W.G.M., van der Pluijm, Gabri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959502/
https://ncbi.nlm.nih.gov/pubmed/17724140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070168
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