Lack of Noggin Expression by Cancer Cells Is a Determinant of the Osteoblast Response in Bone Metastases

Prostate and mammary cancer bone metastases can be osteoblastic or osteolytic, but the mechanisms determining these features are unclear. Bone morphogenetic and Wnt proteins are osteoinductive molecules. Their activity is modulated by antagonists such as noggin and dickkopf-1. Differential expressio...

Full description

Saved in:
Bibliographic Details
Main Authors: Schwaninger, Ruth, Rentsch, Cyrill A., Wetterwald, Antoinette, van der Horst, Geertje, van Bezooijen, Rutger L., van der Pluijm, Gabri, Löwik, Clemens W.G.M., Ackermann, Karin, Pyerin, Walter, Hamdy, Freddie C., Thalmann, George N., Cecchini, Marco G.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2007
Subjects:
Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762703/
https://ncbi.nlm.nih.gov/pubmed/17200191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.051276
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items