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The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms
Here we characterize the consequences of elevated bone morphogenetic protein (BMP) signaling on neural tube morphogenesis by analyzing mice lacking the BMP antagonist, Noggin. Noggin is expressed dorsally in the closing neural folds and ventrally in the notochord and somites. All Noggin(−/−) pups ar...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3001110/ https://ncbi.nlm.nih.gov/pubmed/16712836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.03.051 |
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