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The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms

Here we characterize the consequences of elevated bone morphogenetic protein (BMP) signaling on neural tube morphogenesis by analyzing mice lacking the BMP antagonist, Noggin. Noggin is expressed dorsally in the closing neural folds and ventrally in the notochord and somites. All Noggin(−/−) pups ar...

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書誌詳細
主要な著者: Stottmann, Rolf W., Berrong, Mark, Matta, Karen, Choi, Murim, Klingensmith, John
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001110/
https://ncbi.nlm.nih.gov/pubmed/16712836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.03.051
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