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The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling

Repulsive guidance molecule b (RGMb) is a bone morphogenetic protein (BMP) coreceptor and sensitizer of BMP signaling, highly expressed in adult dorsal root ganglion (DRG) sensory neurons. We used a murine RGMb knock-out to gain insight into the physiological role of RGMb in the DRG, and address whe...

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Detalhes bibliográficos
Main Authors: Ma, Chi H. E., Brenner, Gary J., Omura, Takao, Samad, Omar A., Costigan, Michael, Inquimbert, Perrine, Niederkofler, Vera, Salie, Rishard, Sun, Chia Chi, Lin, Herbert Y., Arber, Silvia, Coppola, Giovanni, Woolf, Clifford J., Samad, Tarek A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243947/
https://ncbi.nlm.nih.gov/pubmed/22171041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4550-11.2011
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