Dragon (RGMb) inhibits interleukin (IL)-6 expression in macrophages

Repulsive guidance molecule (RGM) family members RGMa, RGMb/Dragon and RGMc/hemojuvelin were recently found to act as BMP co-receptors that enhance BMP signaling activity. While our previous studies have shown that hemojuvelin regulates hepcidin expression and iron metabolism through the BMP pathway...

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Hlavní autoři: Xia, Yin, Cortez-Retamozo, Virna, Niederkofler, Vera, Salie, Rishard, Chen, Shanzhuo, Samad, Tarek, Hong, Charles C., Arber, Silvia, Vyas, Jatin M., Weissleder, Ralph, Pittet, Mikael J., Lin, Herbert Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670585/
https://ncbi.nlm.nih.gov/pubmed/21187450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002047
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