A Genome-Wide Association Study Identifies Susceptibility Loci for Ovarian Cancer at 2q31 and 8q24

Ovarian cancer (OC) accounts for more deaths than all other gynecological cancers combined. To identify common low-penetrance OC susceptibility genes, we conducted a genome-wide association study (GWAS) of 507,094 SNPs in 1,768 cases and 2,354 controls, with follow-up of 21,955 SNPs in 4,162 cases a...

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Detalhes bibliográficos
Main Authors: Goode, Ellen L., Chenevix-Trench, Georgia, Song, Honglin, Ramus, Susan J., Notaridou, Maria, Lawrenson, Kate, Widschwendter, Martin, Vierkant, Robert A., Larson, Melissa C., Kjaer, Susanne K., Birrer, Michael J., Berchuck, Andrew, Schildkraut, Joellen, Tomlinson, Ian, Kiemeney, Lambertus A., Cook, Linda S., Gronwald, Jacek, Garcia-Closas, Montserrat, Gore, Martin E., Campbell, Ian, Whittemore, Alice S., Sutphen, Rebecca, Phelan, Catherine, Anton-Culver, Hoda, Pearce, Celeste Leigh, Lambrechts, Diether, Rossing, Mary Anne, Chang-Claude, Jenny, Moysich, Kirsten B., Goodman, Marc T., Dörk, Thilo, Nevanlinna, Heli, Ness, Roberta B., Rafnar, Thorunn, Hogdall, Claus, Hogdall, Estrid, Fridley, Brooke L., Cunningham, Julie M., Sieh, Weiva, McGuire, Valerie, Godwin, Andrew K., Cramer, Daniel W., Hernandez, Dena, Levine, Douglas, Lu, Karen, Iversen, Edwin S., Palmieri, Rachel T., Houlston, Richard, van Altena, Anne M., Aben, Katja K.H., Massuger, Leon F.A.G., Brooks-Wilson, Angela, Kelemen, Linda E., Le, Nhu D., Jakubowska, Anna, Lubinski, Jan, Medrek, Krzysztof, Stafford, Anne, Easton, Douglas F., Tyrer, Jonathan, Bolton, Kelly L., Harrington, Patricia, Eccles, Diana, Chen, Ann, Molina, Ashley N., Davila, Barbara N., Arango, Hector, Tsai, Ya-Yu, Chen, Zhihua, Risch, Harvey A., McLaughlin, John, Narod, Steven A., Ziogas, Argyrios, Brewster, Wendy, Gentry-Maharaj, Aleksandra, Menon, Usha, Wu, Anna H., Stram, Daniel O., Pike, Malcolm C., Beesley, Jonathan, Webb, Penelope M., Chen, Xiaoqing, Ekici, Arif B., Thiel, Falk C., Beckmann, Matthias W., Yang, Hannah, Wentzensen, Nicolas, Lissowska, Jolanta, Fasching, Peter A., Despierre, Evelyn, Amant, Frederic, Vergote, Ignace, Doherty, Jennifer, Hein, Rebecca, Wang-Gohrke, Shan, Lurie, Galina, Carney, Michael E., Thompson, Pamela J., Runnebaum, Ingo, Hillemanns, Peter, Dürst, Matthias, Antonenkova, Natalia, Bogdanova, Natalia, Leminen, Arto, Butzow, Ralf, Heikkinen, Tuomas, Stefansson, Kari, Sulem, Patrick, Besenbacher, Sören, Sellers, Thomas A., Gayther, Simon A., Pharoah, Paul D.P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020231/
https://ncbi.nlm.nih.gov/pubmed/20852632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.668
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