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Allelic Analysis of Serous Ovarian Carcinoma Reveals Two Putative Tumor Suppressor Loci at 18q22-q23 Distal to SMAD4, SMAD2, and DCC

The distal half of chromosome arm 18q is frequently lost in ovarian carcinoma. To define the putative tumor suppressor locus/loci more precisely we performed allelic analysis with 27 polymorphic microsatellite markers located at 18q12.3-q23 in 64 serous and 9 mucinous ovarian carcinomas. Fifty-nine...

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Bibliographische Detailangaben
Hauptverfasser: Lassus, Heini, Salovaara, Reijo, Aaltonen, Lauri A., Butzow, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850432/
https://ncbi.nlm.nih.gov/pubmed/11438451
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