Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

BACKGROUND: Genome-wide association studies (GWAS) have identified 18 loci associated with serous ovarian cancer (SOC) susceptibility but the biological mechanisms driving these findings remain poorly characterised. Germline cancer risk loci may be enriched for target genes of transcription factors...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Kar, Siddhartha P, Adler, Emily, Tyrer, Jonathan, Hazelett, Dennis, Anton-Culver, Hoda, Bandera, Elisa V, Beckmann, Matthias W, Berchuck, Andrew, Bogdanova, Natalia, Brinton, Louise, Butzow, Ralf, Campbell, Ian, Carty, Karen, Chang-Claude, Jenny, Cook, Linda S, Cramer, Daniel W, Cunningham, Julie M, Dansonka-Mieszkowska, Agnieszka, Doherty, Jennifer Anne, Dörk, Thilo, Dürst, Matthias, Eccles, Diana, Fasching, Peter A, Flanagan, James, Gentry-Maharaj, Aleksandra, Glasspool, Rosalind, Goode, Ellen L, Goodman, Marc T, Gronwald, Jacek, Heitz, Florian, Hildebrandt, Michelle A T, Høgdall, Estrid, Høgdall, Claus K, Huntsman, David G, Jensen, Allan, Karlan, Beth Y, Kelemen, Linda E, Kiemeney, Lambertus A, Kjaer, Susanne K, Kupryjanczyk, Jolanta, Lambrechts, Diether, Levine, Douglas A, Li, Qiyuan, Lissowska, Jolanta, Lu, Karen H, Lubiński, Jan, Massuger, Leon F A G, McGuire, Valerie, McNeish, Iain, Menon, Usha, Modugno, Francesmary, Monteiro, Alvaro N, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Paul, James, Pearce, Celeste L, Pejovic, Tanja, Permuth, Jennifer B, Phelan, Catherine, Pike, Malcolm C, Poole, Elizabeth M, Ramus, Susan J, Risch, Harvey A, Rossing, Mary Anne, Salvesen, Helga B, Schildkraut, Joellen M, Sellers, Thomas A, Sherman, Mark, Siddiqui, Nadeem, Sieh, Weiva, Song, Honglin, Southey, Melissa, Terry, Kathryn L, Tworoger, Shelley S, Walsh, Christine, Wentzensen, Nicolas, Whittemore, Alice S, Wu, Anna H, Yang, Hannah, Zheng, Wei, Ziogas, Argyrios, Freedman, Matthew L, Gayther, Simon A, Pharoah, Paul D P, Lawrenson, Kate
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Genetics & Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318969/
https://ncbi.nlm.nih.gov/pubmed/28103614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.426
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