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A novel germline PALB2 deletion in Polish breast and ovarian cancer patients

BACKGROUND: PALB2 protein was recently identified as a partner of BRCA1 and BRCA2 which determines their proper function in DNA repair. METHODS: Initially, the entire coding sequence of the PALB2 gene with exon/intron boundaries was evaluated by the PCR-SSCP and direct sequencing methods on 70 ovari...

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Main Authors: Dansonka-Mieszkowska, Agnieszka, Kluska, Anna, Moes, Joanna, Dabrowska, Michalina, Nowakowska, Dorota, Niwinska, Anna, Derlatka, Pawel, Cendrowski, Krzysztof, Kupryjanczyk, Jolanta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829009/
https://ncbi.nlm.nih.gov/pubmed/20122277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-20
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