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A novel germline PALB2 deletion in Polish breast and ovarian cancer patients
BACKGROUND: PALB2 protein was recently identified as a partner of BRCA1 and BRCA2 which determines their proper function in DNA repair. METHODS: Initially, the entire coding sequence of the PALB2 gene with exon/intron boundaries was evaluated by the PCR-SSCP and direct sequencing methods on 70 ovari...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829009/ https://ncbi.nlm.nih.gov/pubmed/20122277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-20 |
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