Evaluation of Diarylureas for Activity Against Plasmodium falciparum

[Image: see text] A library of diarylurea insulin-like growth factor 1 receptor inhibitors was screened for activity against chloroquine-sensitive (3D7) and chloroquine-resistant (K1) strains of Plasmodium falciparum. The 4-aminoquinaldine-derived diarylureas displayed promising antimalarial potency...

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Hlavní autoři: Zhang, Yiqun, Anderson, Marc, Weisman, Jennifer L., Lu, Min, Choy, Cindy J., Boyd, Vincent A., Price, Jeanine, Sigal, Martina, Clark, Julie, Connelly, Michele, Zhu, Fangyi, Guiguemde, W. Armand, Jeffries, Cynthia, Yang, Lei, Lemoff, Andrew, Liou, Ally P., Webb, Thomas R., DeRisi, Joseph L., Guy, R. Kiplin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2010
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019604/
https://ncbi.nlm.nih.gov/pubmed/21243104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100083c
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