Evaluation of Diarylureas for Activity Against Plasmodium falciparum

[Image: see text] A library of diarylurea insulin-like growth factor 1 receptor inhibitors was screened for activity against chloroquine-sensitive (3D7) and chloroquine-resistant (K1) strains of Plasmodium falciparum. The 4-aminoquinaldine-derived diarylureas displayed promising antimalarial potency...

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Detalhes bibliográficos
Main Authors: Zhang, Yiqun, Anderson, Marc, Weisman, Jennifer L., Lu, Min, Choy, Cindy J., Boyd, Vincent A., Price, Jeanine, Sigal, Martina, Clark, Julie, Connelly, Michele, Zhu, Fangyi, Guiguemde, W. Armand, Jeffries, Cynthia, Yang, Lei, Lemoff, Andrew, Liou, Ally P., Webb, Thomas R., DeRisi, Joseph L., Guy, R. Kiplin
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019604/
https://ncbi.nlm.nih.gov/pubmed/21243104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100083c
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