Evaluation of Diarylureas for Activity Against Plasmodium falciparum

[Image: see text] A library of diarylurea insulin-like growth factor 1 receptor inhibitors was screened for activity against chloroquine-sensitive (3D7) and chloroquine-resistant (K1) strains of Plasmodium falciparum. The 4-aminoquinaldine-derived diarylureas displayed promising antimalarial potency...

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Autors principals: Zhang, Yiqun, Anderson, Marc, Weisman, Jennifer L., Lu, Min, Choy, Cindy J., Boyd, Vincent A., Price, Jeanine, Sigal, Martina, Clark, Julie, Connelly, Michele, Zhu, Fangyi, Guiguemde, W. Armand, Jeffries, Cynthia, Yang, Lei, Lemoff, Andrew, Liou, Ally P., Webb, Thomas R., DeRisi, Joseph L., Guy, R. Kiplin
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2010
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019604/
https://ncbi.nlm.nih.gov/pubmed/21243104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100083c
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