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The polynuclear platinum BBR3610 induces G2/M arrest and autophagy early and apoptosis late in glioma cells
BBR3610 is a polynuclear platinum compound, in which two platinums are linked by a spermine-like linker, and studies in a variety of cancers, including glioma, have shown that it is more potent than conventional platinums and works by different means. Identifying the mechanism of action of BBR3610 w...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018945/ https://ncbi.nlm.nih.gov/pubmed/20713409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq095 |
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