Conformational Modulation of Iduronic Acid-Containing Sulfated Glycosaminoglycans by a Polynuclear Platinum Compound. Implications for Development of Antimetastatic Platinum Drugs.

(1)H NMR spectroscopic studies on the 1:1 adduct of the pentasaccharide Fondaparinux (FPX) and the substitution-inert polynuclear platinum complex TriplatinNC show significant modulation of geometry around the glycosidic linkages of the FPX constituent monosaccharides. FPX is a valid model for the h...

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Enregistré dans:
Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Gorle, Anil K., Haselhorst, Thomas, Katner, Samantha J., Everest-Dass, Arun V., Hampton, James D., Peterson, Erica J., Koblinski, Jennifer E., Katsuta, Eriko, Takabe, Kazuaki, von Itzstein, Mark, Berners-Price, Susan J., Farrell, Nicholas P.
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902481/
https://ncbi.nlm.nih.gov/pubmed/33174390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202013749
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