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Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

Single molecule and NMR measurements of protein dynamics increasingly uncover the complexity of binding scenarios. Here we describe an extended conformational selection model which embraces a repertoire of selection and adjustment processes. Induced fit can be viewed as a subset of this repertoire,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Csermely, Peter, Palotai, Robin, Nussinov, Ruth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018770/
https://ncbi.nlm.nih.gov/pubmed/20541943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2010.04.009
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